Blood Cancer Journal, Published online: 02 June 2026; doi:10.1038/s41408-026-01531-wChimeric antigen receptor T-cell therapy is equally effective and safe in older (≥70) and younger patients with mult
Leukemia, Published online: 02 June 2026; doi:10.1038/s41375-026-02982-7Sphingosine-1-phosphate receptor modulators resensitize FLT3-ITD acute myeloid leukemia cells with NRAS mutations to FLT3 inhibi
Leukemia, Published online: 01 June 2026; doi:10.1038/s41375-026-02991-6TP53 deficiency in AML induces resistance to T-cell engagers through an immunosuppressive secretome
The recent fifth edition of World Health Organization and International Consensus Classification in 2022 recognized TP53-mutated myelodysplastic neoplasms (MDS) as a distinct entity requiring multi-hi
Blood Cancer Journal, Published online: 01 June 2026; doi:10.1038/s41408-026-01534-7Prognostic impact of morphological lymphocyte counts on aggressive adult T-cell leukemia/lymphoma: Japan ATL nationw
供者淋巴细胞输注（DLI）是应对异基因造血干细胞移植（allo-HCT）后复发的重要策略。本研究回顾分析了2010至2022年间，83名在移植后复发并接受DLI的急性白血病或骨髓增生异常综合征（MDS）成年患者。通过每月检测嵌合度和基因标志物，将治疗分为“抢先治疗”（在分子复发时进行）和“常规治疗”（在明显的血液学复发时进行）。 生存分析表明，常规治疗组的生存率显著劣于抢先治疗组，其中常规治疗组