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血液病科普知识、最新研究进展与患者关怀

Prof. Richard T Silver—Pioneer of MPN 18 January, 1929–17 April, 2026

Prof. Richard T Silver—Pioneer of MPN 18 January, 1929–17 April, 2026

Leukemia, Published online: 26 June 2026; doi:10.1038/s41375-026-03008-yProf. Richard T Silver—Pioneer of MPN 18 January, 1929–17 April, 2026

From data to evidence: why administrative databases alone cannot measure real-world effectiveness in rare diseases – the case of chronic myeloid leukaemia

From data to evidence: why administrative databases alone cannot measure real-world effectiveness in rare diseases – the case of chronic myeloid leukaemia

Leukemia, Published online: 26 June 2026; doi:10.1038/s41375-026-03037-7From data to evidence: why administrative databases alone cannot measure real-world effectiveness in rare diseases – the case of

The case for prospective <i>MEN1</i> surveillance in the era of sequential menin inhibitor therapy

The case for prospective <i>MEN1</i> surveillance in the era of sequential menin inhibitor therapy

Leukemia, Published online: 25 June 2026; doi:10.1038/s41375-026-03023-zThe case for prospective MEN1 surveillance in the era of sequential menin inhibitor therapy

Integrated transcriptomic and TCR profiling reveals local immune dysregulation of T cells in Gl aGvHD

Integrated transcriptomic and TCR profiling reveals local immune dysregulation of T cells in Gl aGvHD

Bone Marrow Transplantation, Published online: 25 June 2026; doi:10.1038/s41409-026-02942-wIntegrated transcriptomic and TCR profiling reveals local immune dysregulation of T cells in Gl aGvHD

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什么是骨髓增生异常综合征（MDS）？

MDS是一组起源于造血干细胞的克隆性疾病，表现为骨髓无法正常生产足够的健康血细胞。常见症状包括贫血、感染和出血倾向。

什么是移植物抗宿主病（GVHD）？

GVHD是异基因造血干细胞移植后最常见的严重并发症，发生率约20%-50%。移植的供者免疫细胞将患者身体组织视为异物进行攻击。

TP53基因突变意味着什么？

TP53突变是MDS中预后最差的分子标志之一。携带该突变的患者对常规化疗反应差，目前靶向药物研发正在进行中。

血液病患者的饮食建议？

保证充足蛋白质摄入，多吃新鲜蔬果补充维生素和铁质，避免生冷食物减少感染风险，化疗期间选择易消化高营养食物。

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