· 自动抓取 · 最新研究
揭秘B细胞急性淋巴细胞白血病双靶点CAR-T疗法复发的细胞与分子机制
B细胞急性淋巴细胞白血病（B-ALL）是一种起源于B细胞的血液系统恶性肿瘤。近年来，同时瞄准CD19和CD22两个靶点的“双靶向”CAR-T细胞疗法（一种经过基因工程改造，能精准识别并杀灭癌细胞的免疫疗法）在治疗此类白血病中展现出巨大潜力。然而，部分患者在治疗后依然会面临疾病复发（Relapse，即肿瘤再次出现）的困境。 为了找出导致复发的“元凶”，研究人员深入探究了其背后的细胞和分子机制。他们
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血液病科普知识、最新研究进展与患者关怀
· 自动抓取 · 最新研究骨髓增殖性肿瘤合并慢性髓系白血病：JAK2靶向治疗与额外突变的潜在影响
本研究深入探讨了骨髓增殖性肿瘤（Myeloproliferative Neoplasm, MPN）同时合并慢性髓系白血病（Chronic Myeloid Leukemia, CML）这一极其罕见病例背后的“克隆动态”与“治疗压力”机制。通俗来讲，就是观察患者体内不同癌细胞群（即不同“克隆”）在受到药物打击时的相互博弈和消长变化。研究发现，针对特定基因（如 JAK2）的靶向治疗以及体内其他额外基因突
· 自动抓取 · 最新研究Monoclonal gammopathy of clinical significance: a multisystem review
Blood Cancer Journal, Published online: 29 May 2026; doi:10.1038/s41408-026-01528-5Monoclonal gammopathy of clinical significance: a multisystem review
· 自动抓取 · 最新研究Functional Outcomes and Quality of Life after unilateral MRgFUS Subthalamotomy in Parkinson's Disease.
Parkinson's disease (PD) leads to progressive motor and non-motor deficits that compromise activities of daily living (ADL) and quality of life (QoL). Although bilateral deep brain stimulation (DBS) o
· 自动抓取 · 最新研究Cardiotoxicity induced by multiple myeloma therapies: mechanistic convergence across proteasome inhibitors, CAR-T, and bispecific antibodies
Blood Cancer Journal, Published online: 29 May 2026; doi:10.1038/s41408-026-01481-3Cardiotoxicity induced by multiple myeloma therapies: mechanistic convergence across proteasome inhibitors, CAR-T, an
· 自动抓取 · 最新研究Advances in Digital Pathology and Artificial Intelligence in the Diagnosis of Myeloid Neoplasms.
Recent advances in digital pathology and artificial intelligence (AI) are transforming our ability to diagnose myeloid neoplasms, including acute myeloid leukemia (AML), myelodysplastic syndromes (MDS